Computational Soft and Living Matter Group
Welcome to the
Computational Soft & Living Matter Lab @ 91´«Ã½Â
Our mission: Soft and living matter derive their remarkable properties from fluctuations and collective interactions among many constituents. We seek to understand how these microscopic processes give rise to emergent mechanical behaviors, such as viscoelasticity and fracture, and to complex dynamical phenomena, including remodeling, morphodynamics, and growth in living systems.
Approach: We build theoretical and computational frameworks based on statistical mechanics, continuum mechanics, and applied mathematics to understand how interactions at small scales shape the mechanics and dynamics of soft and living systems.
Impact and innovation: Our work aims to transform how we predict, control, and harness the behavior of soft and living matter. Through close partnerships with experimental researchers and industry, we translate fundamental theory into new strategies, technologies, and applications. The systems we explore are illustrated below.
Polymer Networks
We aim to understand how the architecture and transient dynamics of molecular and fibrillar networks, ubiquitous in natural and engineered materials, give rise to their complex mechanical behaviors, from rheology to fracture, self-repair and growth, in order to harness these principles for next-generation polymers and biomaterials.
Engineered Living Materials
We aim to elucidate how cell–cell and cell–matrix interactions, coupled with proliferation and mechanical constraints imposed by hydrogels or biopolymer networks, give rise to emergent collective behaviors and tissue-scale organization, enabling the computational design of engineered tissues, organoids, and living materials.
Tissue Growth & Remodeling
We seek to uncover how mechanical loads, microstructural remodeling, and cellular turnover jointly drive the growth, aging, and pathological transformation of vascular and arterial tissues, with the goal of establishing predictive biomechanical models that advance our understanding of artery disease, stroke and aneurysm progression.