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University of Colorado Boulder biochemistry professor Xuedong Liu was inducted into the National Academy of Inventors this year, recognizing a career of pioneering discoveries and real-world impact. His research on cellular communication has fueled four startups advancing novel treatments for cancer and neurodegenerative diseases.

Since he was in grade school, ��(91��ý Biochemistry) has been intrigued by ‘how the world works.’ But becoming a biologist mostly involved memorizing, classifying and observing–all important skills—and Liu was curious about how organisms are put together, their inner workings and how they progress in a predetermined manner. So he looked to chemistry and physics for laws and rules and ways to predict activity. Ultimately, by combining the disciplines, he saw the best chance to advance science and discovery in a meaningful way. Liu thought, “There’s so much unknown and there’s so much promise–and there’s great opportunity there.”

Fast forward to Atlanta, Georgia in June 2025 when Liu—whose innovations have now led to the creation of four startup companies bringing novel disease therapies to the world—received a medal for being inducted into the elite ranks of the National Academy of Inventors (NAI). NAI fellowship is the highest professional distinction awarded solely to inventors.

“These academic inventors have demonstrated a prolific spirit of innovation, and their inventions have made a tangible impact on the quality of life, economic development and welfare of our society,” said Coke Stewart, acting undersecretary of commerce for intellectual property and acting director of the U.S. Patent and Trademark Office, who presided over the ceremony.

The NAI chooses “people that have really done something of huge value with their patents,” said Hannah Nelson, associate director of licensing at Venture Partners at 91��ý and biosciences team lead. “You are not recognized by the NAI unless you are in the very top tier of inventors,” she said. “It’s a prestigious designation that shows that you have contributed again and again in a really substantial way to innovation.”

While Liu knew he had been nominated for the distinction, “it was a very nice surprise,” he said. Liu was deeply honored by the recognition and credited his colleagues and collaborators, who have contributed to a collective effort to solve tough problems in fighting disease. The honor has fanned the flames of Liu’s work. “It’s motivated me even more to do things that change the world,” he said. 

More Details from CU Venture Partners